Brain abscess is outside infection through blood diffusion , direct spread , trauma, infections and other ways to invade brain tissue caused by a serious life -threatening infections in patients in recent years, although the overall incidence and mortality decreased significantly [ 1 ] , but still Some lack of neurological symptoms and signs of patients with a diagnosis of unknown delays in treatment , now 30 patients in our hospital clinical features and imaging results reported below , aimed at raising awareness of the disease .脑发炎脓肿为外界感染经过血行廓张、直接漫延、外因感触而悲伤染等路径进入境内脑团体所致,是一种威胁到患者性命的严重感染,近年来,固然总体发病率和病故率表面化减退[1],但仍有一点匮缺神经体系症状.
Materials and Methods
1 General Information
April 1993 - December 2007 in our hospital 30 cases of brain abscess patients , 21 males and 9 females , aged 9-68 years, mean age of 316 years , the treatment time onset 3d-2 months , all patients both by CT and ( or ) magnetic resonance imaging (MRI) examination , clinical diagnosis of brain abscess and pathologically anti-infective therapy and clinical results were confirmed. Brain abscess pathogens : otogenic brain abscess in 6 cases, 4 cases of blood-borne , rhinogenous two cases , traumatic eight cases , 10 cases of cryptogenic .1993年四月~2007年十二月在我院住院的30例脑发炎脓肿患者,男21例,女9例,岁数9-68岁,均匀岁数316岁,就医时间发病3d-2个月,所有病例均经头颅CT和(或)磁共振成像(MRI)查缉,临床明诊断确实断为脑发炎脓肿并经切除缝合病理及临床抗感染医治最后结果对照证明。
2 , the clinical manifestations
The main clinical manifestations : headache , vomiting , papilledema , increased intracranial pressure symptoms ( 14 cases 46.66% ) , fever ( 15 cases 50% ) , hemiplegia ( 6 cases 20% ) , other symptoms of disturbance of consciousness , cranial nerve anesthesia addiction, meningeal irritation , seizures and mental disorders.
3 , laboratory tests ;
Blood tests : WBC (10 ~ 20) × 109 / L 13 cases, more than 20 × 109 / L 6 cases, 14 cases of normal ( 43% ) .
CSF : 30 patients with cerebrospinal fluid examination , abnormal six cases , the appearance of purulent changed three cases , eight cases of bacterial antigen tests were negative , five cases of cerebrospinal fluid culture were negative .
4 , EEG , abnormal 11 cases ( 35% ) , showed bilateral leads slow ( five cases ) or limited to Board of slow wave ( 6 cases ) .
Result
30 patients with CT plain and enhanced inspection , including 10 cases by MRI , and get position and ( or ) qualitative diagnosis . CT scan showed low density irregular flakes , fuzzy boundaries, mass effect is not obvious, 6 cases ( 20% ) ; injection of contrast agent , no enhancement 2 cases ( 6.66% ) , patchy , gyri like enhancement four cases ( 13.3% ) ; scan showed oval cystic low density 20 cases ( 66.66% ) , of which 6 cases ( 20% ) with liquid gas inside the plane , surrounded with a slightly higher density than regular grade thick wall , varying wall thickness , wall thickness 1 ~ 3mm in 18 cases ( 60% ) , 3 ~ 6mm wall thickness of 12 patients ( 40% ) , most peripheral edema flake density , injection of contrast agent , capsule annular enhancement, thick-walled hollow circular shadow . Figure ( 1-4 ) . Central MRI scan showed lesions showed low T1W1, high T2W1 signal has high or slightly higher signal annular wall , posterior enhancement significantly enhanced , more clearly, no enhancement of the lesion central figure ( 5-8 ) .
Imaging brain abscess : are the parietal lobe and the main junction . 12 cases in the frontal lobe , parietal lobe in 7 cases, 6 cases of temporal lobe , occipital lobe in 3 cases, 2 cases of cerebellar hemisphere . 30 cases, 21 cases of solitary abscess ( 70% ) , multiple 9 cases ( 30% ) ; abscess diameter <1.5 cm 21例, 1.5 ~ 4 cm 4例,> 4 cm 5 cases
Discuss
The etiology of brain abscess greater than the change in the past few decades , brain abscess caused by Staphylococcus aureus decreased, while Gram-negative bacteria and anaerobic bacteria caused an increased incidence of brain abscess [ 2 ] , is a compromise serious infections in patients with life since its inception in CT , because of its early diagnosis , accurate positioning and dynamic observation, the brain abscess mortality decreased from 40% to 5 % -10% [ 3 ] . In recent years, although the overall incidence and mortality decreased significantly, but there are still some lack of neurological symptoms and signs of the cases the diagnosis is unknown due to delays in treatment , brain abscess infection pathogens are three categories, namely pyogenic bacteria, fungi and protozoa , the former most common. Infection through acute encephalitis , purulent and capsule formation three phases eventually formed brain abscess, more time in a month or so, the typical clinical manifestations should have fever, headache and signs of nervous system orientation triad , the group only 9 cases ( 27% ) , with the reported 28% match. It is noteworthy that 50% of this group of patients is always normal body temperature , headache, accounting for 46.66% of the nervous system signs of localization , 30% , and therefore should be highly vigilant clinically atypical brain abscess, because many patients had irregular use of antibiotics , the clinical symptoms are typically , brain abscess and ring enhancement ring with other brain lesions [ 4 ] requires identification. Brain abscess : blood-borne infections occur in the cerebral hemispheres , in the middle cerebral artery area is more common , ear -borne infection often occurs in the ipsilateral frontal or cerebellar abscess can be divided into single rooms , single, single room multiple, multi-room -prone in different forms . Abstract Objective To analyze the clinical features of brain abscess , improve their understanding of CT and MRI . Methods 30 patients with suspected or follow-up of patients with brain abscess underwent CT and MRI , 21 males and 9 females , clinically characterized by headache, vomiting , papilledema , increased intracranial pressure . The results showed typical CT hypodense clear boundary , enhanced abscess capsule showed a uniform annular high-density zone , abscesses central constant density : MRI manifestations Central abscess on T1 and T2 -weighted imaging are low signal envelope is high signal to clear boundary ring , all have a smooth wall abscess low signal "dark zone" enhanced scan see abscess wall showed ring enhancement of uniform thickness , the inner edge smooth. Conclusion brain abscess CT, MRI , and some characteristics , and is sensitive , accurate and fast way to check eyelashes , applicable to all parts of the brain abscess.